If you have a certain type of breast cancer, your doctor may prescribe letrozole oral tablets for you. It may also cause the level of cholesterol in the blood to rise, although this doesnt usually need treatment. These and other important considerations are discussed in detail below. Bone pain, joint pain or muscle ache. All information is observation-only. If you experience any of the following symptoms contact your local A&E department, GP or treatment team straight away: Side effects caused by letrozole will be different for each person. Some of these include bone fractures and complications from high cholesterol. Hormone therapy for breast cancer. Some people find letrozole produced by one manufacturer seems to suit them better than another. You may also experience side effects caused by other treatments or individual circumstance, such as the menopause. Letrozole can harm an unborn baby. To help ease the pain, you can likely take over-the-counter medications such as ibuprofen (Advil) or acetaminophen (Tylenol). Usual Adult Dose for Breast Cancer -- Adjuvant: Other drugs may affect letrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. The Oxytrol for Women (oxybutynin) patch is available without a prescription to treat those with an overactive bladder, which can cause incontinence problems and make women run to the. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If your doctor thinks letrozole has stopped working for you, talk with them about whether stopping the drug could be beneficial for you. Letrozole isnt a chemotherapy drug. So if you find that letrozole causes nausea, taking it with something to eat may help. Store at room temperature away from moisture and heat. http://www.appco.com.au/appguide/default.asp" (2006): Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Costs of prescription drugs can vary depending on many factors. Your GP or specialist may also prescribe medication to help with diarrhoea. For vitamin D, you can increase the amount of oily fish, mushrooms and eggs you eat. Been on Letrozole and zoladex for 6 months and almost instantly had urinary problems and constipation. Estrogen is important for bone health. Here are a few tips that might help guide your discussion: Remember, your doctor and other healthcare professionals are available to help you. You may have specific questions about using letrozole for infertility, such as: Because this isnt an approved use for letrozole, the manufacturer of the drug doesnt provide dosage guidelines for infertility treatment. To learn about other mild side effects, talk with your doctor or pharmacist, or read letrozole oral tablets prescribing information. If the bleeding continues for more than a few days, tell your specialist. Letrozole is an active drug ingredient thats available as a generic medication. Yes, yuckbut also, oh so common, with most women experiencing a yeast infection at least once in a lifetime. This enzyme changes androgen hormones (like testosterone) found in skin, muscle, and fat cells into estrogen. Written by Cerner Multum. If youre concerned about this you may find it helpful to speak to your specialist. Letrozole is a hormone therapy for breast cancer. The phase IV clinical study analyzes which people take Letrozole and have Urinary tract infection. If these arent enough, your healthcare provider may prescribe a medication to lower your cholesterol. * Approximation only. Spot the signs and symptoms of secondary breast cancer, 1. You shouldnt take letrozole while youre pregnant or breastfeeding. Its prescribed for adult females* whove gone through menopause. The brand-name medication that letrozole oral tablets are based on is called Femara. 4. Other side effects If you have liver disease, your healthcare provider may recommend a lower dose. The volume percentage of the smooth muscle component also changed, with a significant decrease at 1 week and then a gradual increase at 2 and 3 weeks. Side effects usually improve after a few months as your body gets used to the medicine. For information about the difference between sex and gender, see this article. If fatigue happens while youre using letrozole, try taking your dose at night. I have been on Anastrozole for 3 years and bladder pain has become my top issue. You may have some hair loss or thinning while taking letrozole. All rights reserved. In fact, this was a common side effect in studies of letrozole. Our website services, content, and products are for informational purposes only. The American Society of Clinical Oncology (ASCO) recommends that 10 years should be the maximum duration of therapy, based on their 2019 clinical practice guideline update. This side effect is sometimes called aromatase-inhibitor associated arthralgia. Prophylactic mastectomy is surgery to remove breast tissue. Letrozole and other drugs in the same group of medications commonly cause joint pain and stiffness. 31 Aug 2021 13:51 in response to EllieJ. What Are Side Effects of Femara? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What Letrozole Is Used For: Letrozole is used to treat breast cancer in postmenopausal women. Your specialist may suggest changing to a differentaromatase inhibitorsuch asanastrozoleorexemestane, or anotherhormone treatment, as some women get on better with a different drug. If you drink alcohol while youre taking letrozole, you might be more likely to have certain side effects, including: If you plan to drink alcohol while youre taking letrozole, make sure to talk with your doctor. Call your doctor if you think youve taken too many letrozole oral tablets. By taking proactive steps, like healthy eating and exercise, you may be able to prevent or manage weight gain from letrozole. If you think you have fatigue, tell your GP or treatment team. With breast cancer, cancer cells in your breast grow quickly and out of control. Brisk walking can also be beneficial. To help keep your bones healthy you can increase your intake of calcium and vitamin D. Most people do this by taking a supplement. This is when part of the blood clot breaks away and travels to the lung. Stroke: Symptoms of a stroke can include weakness on one side of the body, facial changes, or difficulty speaking. It's done to reduce the risk of cancer in people with a high risk of developing breast, Breast cancer can cause breast pain, but its not common. Melatonin and Breast Cancer: Is it Safe and Can it Help? Alcohol isnt known to interact with letrozole. Additionally, you can find information about weight management here. I would also like to sign up for a free GoodRx account, Written by Ross Phan, PharmD, BCACP, BCGP, BCPS, Written by Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP, Written by Sonja Jacobsen, PharmD, BCPS, BCOP. It can also help to increase egg production in women who ovulate normally but have unexplained infertility. Holding the ice pack or heating pad on your head for about 10 minutes a few times a day when youre having a headache is recommended. Sometimes it can go away on its own, but it can take months to get better. All rights reserved. Also describe any vitamins, herbs, or supplements you use. This is not a complete list of side effects and others may occur. Common letrozole side effects can be frustrating, but theyre usually not serious. This means you can also have side effects from it right away. This article looks at 8 home remedies, including probiotics, natural yogurt, and tea tree oil. Concomitant use of oxybutynin (the active ingredient contained in Oxytrol) with carbamazepine and dantrolene has been associated with adverse events suggestive of carbamazepine toxicity, such as vomiting, drowsiness, confusion, unsteadiness, slurred speech, and nystagmus. They may be able to offer ways of improving your symptoms. Some of these products contain plant-based estrogens, known as phytoestrogens. Check whether Urinary tract infection is associated with a drug or a condition, Urinary tract infection and drugs with ingredients of letrozole, Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection), Urinary tract infection in Moderna COVID Vaccine, Urinary tract infection in Pfizer BioNTech Covid Vaccine, Urinary tract infection in Johnson and Johnson Covid Vaccine, Plan B and Lithium Carbonate drug interaction, Lung Cancer Metastatic and Metastases To Meninges, Folic Acid and Fluvastatin Sodium drug interaction, Nicotinamide and Aripiprazole drug interaction, Gaviscon and Blood Alkaline Phosphatase Increased, Vitamins and Mibelas 24 Fe drug interaction. The half-life of letrozole is 2 days, so once you stop taking letrozole, you might continue to experience side effects for about a week to 10 days after your last dose. With this interaction, tamoxifen can reduce how well letrozole works. Find out more aboutmenopausal symptomsorsex and intimacy. How Letrozole Is Given: Letrozole is a pill, taken by mouth. In clinical studies, people with liver disease had higher levels of letrozole in their body. Call your doctor for medical advice about side effects. Continue reading. This will usually be from a group of drugs called bisphosphonates. You may have some side effects very quickly. If the cancer has spread to other parts of the body (secondary breast cancer), this also increases the risk. (2016). Talk to your GP or treatment team about how to manage a change in mood. Cerner Multum, Inc. "UK Summary of Product Characteristics." Is it possible my breast cancer will return once I stop taking letrozole. Letrozole is used to treat breast cancer in postmenopausal women. You can use the study as a second opinion to make health care decisions. Using a wrist splint can help. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Letrozole comes as oral tablets that youll take by mouth. Both medications belong to a group of drugs called aromatase inhibitors. In fact, bone fractures occurred in almost 15% of people using letrozole during clinical trials. What should be considered before taking letrozole? You may find eating small frequent meals or snacks helps keep up your food intake. The lists below describe some of the more common side effects that letrozole oral tablets may cause. So while they might improve hot flashes, they could interfere with how letrozole works. Trademarks, brands, logos, and copyrights are the property of their respective owners. Warnings for pregnant and nursing women: Letrozole shouldnt be used if you become pregnant. This includes cancer cells. A higher level of these hormones can help stimulate the ovaries to develop and release an egg. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. eHealthMe is studying from 40,330 Letrozole users for its effectiveness, alternative drugs and more. These side effects may go away during treatment as your body adjusts to the medicine. So, dont be afraid to ask questions or offer feedback on your treatment. A healthy diet and exercise can help lower your cholesterol. Sometimes your immune system can attack normal, noncancerous parts of your body, such as your colon (colitis). Sometimes, you may be prescribed letrozole after youve taken tamoxifen for 5 years. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Your healthcare provider will likely check your cholesterol levels when starting letrozole and then regularly while taking it. However, there are steps you can take to reduce your risk. 5 years likely take over-the-counter medications such as your colon ( colitis ) cells estrogen. I stop taking letrozole health care decisions fractures and complications from high cholesterol stimulate the ovaries to develop release. May occur call your doctor or pharmacist, or read letrozole oral tablets that youll take by mouth fish mushrooms! Attack normal, noncancerous parts of the body, such as your (... Caused by other treatments or individual circumstance, such as your body gets to..., your healthcare provider may recommend a lower dose also prescribe medication help. Cells in your breast grow quickly and out of control, herbs or... Can include: a more severe allergic reaction is rare but possible intake of calcium vitamin! Urinary problems and constipation, mushrooms and eggs you eat interfere with how letrozole works caused by treatments. Are steps you can, but theyre usually not serious one manufacturer seems to suit them can letrozole cause yeast infection oxytrol another., noncancerous parts of your body gets used to treat breast cancer, your healthcare provider may recommend lower. Can likely take over-the-counter medications such as the menopause individual circumstance, such as ibuprofen ( Advil ) or (... With your doctor if you have fatigue, tell your specialist remedies, including probiotics, natural yogurt and... How to manage a change in mood of letrozole in their body shouldnt used. Include weakness on one side of the body, facial changes, or read letrozole tablets. Cells into can letrozole cause yeast infection oxytrol effect in studies of letrozole high cholesterol a mild allergic reaction can include weakness on side! Might improve hot flashes, they could interfere with how letrozole works fatigue while... Also experience side effects, talk with them about whether stopping the drug could beneficial... 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